Treating Recurrent Vulvovaginal Candidiasis

These U.S. researchers sought to determine the efficacy of fluconazole maintenance therapy for recurrent vulvovaginal candidiasis (VVC) in a manufacturer-funded, multicenter study. First, 494 women (mean age, 34; range, 18-65) with at least four documented episodes of VVC in the previous year and presenting with symptomatic, culture-positive VVC received three doses of oral fluconazole (150 mg at 3-day intervals). Women considered clinically cured at 2 weeks (387 of 422 women) …