Research Progress of T Lymphocytes in Pathogenesis of Graves′ Disease

Graves disease is the most common type of hyperthyroidism,accounting for 85%-90% of the total,the pathogenesis of which is not entirely clear yet.But as an autoimmune thyroid disease,T lymphocytes plays an important role in the pathogenesis.Th1,Th2,Treg and Th1/Th2 cytokines imbalance are closely associated with the pathogenesis of Graves disease.In recent years,Th17 and its related cytokines may play an essential role in the pathogenesis of Graves disease.Here is to make a review on the relationship between Th1,Th2,Th17,Treg and Graves disease.