Tetrabromobisphenol-A (TBBPA) is one of the most widely used brominates flame retardants that has extensively been detected in various environments worldwide.In the present study, the characteristics of co metabolic degradation of TBBPA by a facultative bacterium strain GC were investigated.TBBPA (10 mg L -1 ) could be removed approximately 40% and 60% by strain under aerobic and anoxic conditions after 7 days cultivation.These findings are of vital importance towards building a comprehensive understanding of bacteria in degradation of TBBPA in the aquatic environments.