颠倒
三环
P-糖蛋白
多重耐药
药理学
医学
化学
生物化学
工程类
汽车工程
抗生素
作者
Tao Yu,Rong Zeng,Gui Yu,Bin Pan,Hongwei Li,Jie Gu,Pengfei Zheng,Qi Yan,Qin Ouyang
出处
期刊:RSC medicinal chemistry
[The Royal Society of Chemistry]
日期:2024-01-01
摘要
Based on synthetic methodology-based library, a new class of tricyclic spiroindole derivatives as potent P-glycoprotein inhibitors with excellent tumor multidrug resistance reversal activity was discovered.
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