Visible‐Light‐Induced Rapid Elimination of Antibiotic Resistance Contaminations Using Graphitic Carbon Nitride Tailored with Carrier Confinement Domains

Abstract Solar water disinfection facilitated by photocatalyst has been considered a viable point‐of‐use (POU) method for mitigating antibiotic resistance contaminations at the household or community levels. Here, density functional theory calculations are used to guide the fabrication of a carrier confinement domains (CCD)‐decorated graphitic carbon nitride (CN) photocatalyst. The CCD integration effectively disrupts the electron distribution symmetry of CN, amplifies its local electron density, and facilitates the formation of a long‐range ordered structure, thereby enhancing charge separation efficiency. Importantly, the CCD directs the migration of photogenerated carriers to specific regions upon light illumination, effectively minimizing their spatial proximity. As a result, the overall reactive oxygen species level of the photocatalytic system is markedly elevated, with a twelvefold increase in H 2 O 2 concentration, alongside a significant rise in •O 2 − and •OH steady‐state concentrations. Remarkably, a record‐high disinfection efficiency is attained, successfully inactivating 7 log of antibiotic‐resistant bacteria within 30 min. Additionally, the photocatalyst can be integrated into a continuous‐flow fixed‐bed reactor, facilitating clean water production for up to 60 h at a rate of 121 L m −2 day −1 , highlighting its significant potential for POU applications.