Retinal pigment epithelial detachments in age-related macular degeneration:pathogenesis, manifestation and therapeutic progress

Detachment of the retinal pigment epithelium is a prominent feature of many chorioretinal disease processes, in the elderly the most prevalent of which is age-related macular degeneration (AMD). Understanding the pathogenesis and subtypes of retinal pigment epithelium detachment is essential because each subtype has a specific pathogenesis, natural history, prognosis, and optimal treatment strategy. Key words: Age-related macular degeneration; Retinal pigment epithelial detachment; Choroidal neovascularization