Periostin, osteopontin and asthma

Both periostin and osteopontin belong to extracellular matrix proteins and have various biological functions.Especially in allergic inflammatory diseases, they were involved in different aspects of the pathogenesis of asthma, such as airway inflammation and airway remodeling.Recent studies have shown that periostin and osteopontin play an important role in the assessment and treatment of asthma as emerging biomarkers.This article will elaborate on the new developments of the relationship between periostin, osteopontin and asthma. Key words: Periostin; Osteopontin; Asthma inflammation; Airway remodelling; Treatment