聚丙烯酰胺
剂量学
吸收剂量
拉曼光谱
材料科学
辐照
光谱学
丙烯酰胺
核磁共振
分析化学(期刊)
化学
共聚物
光学
核医学
聚合物
物理
色谱法
医学
核物理学
高分子化学
量子力学
作者
Clive Baldock,Llewellyn Rintoul,Stephen Keevil,J. H. Pope,Graeme A. George
标识
DOI:10.1088/0031-9155/43/12/017
摘要
Polyacrylamide gels (PAGs) are used for magnetic resonance imaging radiation dosimetry. Fourier transform (FT) Raman spectroscopy studies were undertaken to investigate cross-linking changes during the copolymerization of polyacrylamide gels in the spectral range of 200-3500 . Vibrational bands of 1285 and 1256 were assigned to acrylamide and bis-acrylamide single binding modes. Bands were found to decrease in amplitude with increasing absorbed radiation dose as a result of copolymerization. Principal component regression was performed on FT-Raman spectra of PAG samples irradiated to 50 Gy. Two components were found to be sufficient to account for 98.7% of the variance in the data. Cross validation was used to establish the absorbed radiation dose of an unknown PAG sample from the FT-Raman spectra. The calculated correlation coefficient between measured and predictive samples was 0.997 with a standard error of estimate of 0.976 and a standard error of prediction of 1.140. Results demonstrate the potential of FT-Raman spectroscopy for ionizing radiation dosimetry using polyacrylamide gels.
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