Neutral Ti Catalysts for the Intramolecular Hydroamination of Alkenes

Abstract Neutral titanium complexes are well known precatalysts for the inter‐ and intramolecular hydroamination of alkynes. In this publication, we show the capability of several neutral titanium complexes to catalyze intramolecular hydroamination reactions of alkenes. The corresponding pyrrolidine and piperidine products are formed in yields up to 97 %. Among the substrates used, only geminally disubstituted amino alkenes are successfully cyclized. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)