Abstract From the heart wood of Cinnamomum Camphora Sieb., a new lignan, (−)-trans-2-(3,4-dimethoxybenzyl)-3-(3,4,5-trimethoxybenzyl)butyrolactone [I] and 3-hydroxy-5,7-dimethoxy-3′,4′-methylenedioxyflavan [IV], were isolated, and their structures were determined.