The goal of this research work is analysis of chemical compounds of extract of fruit and peel of some local varieties pomegranate ("Qora qayim", "Qizil anor", "Oq dona/Tuyatish", "Achchik dona").The experiments were carried out by using methods of standard chemical synthesis.In the ethanol extract (70%) of the fruit peel of varieties "Qora qayim", "Qizil anor", "Oq dona/Tuyatish", "Achchik dona"were identified vitamins A (0.015-0.063 mg/100 ml), B 1 (0.034-0.064 mg/100 ml), B 2 (0.024-0.052 mg/100 ml), B 5 (0.023-0.038 mg/100 ml), B 6 (0.025-0.082 mg/100 ml), C (4.805-11.546mg/100 ml), and E (0.014-0.612 mg/100 ml), as well as macronutrients (K, Ca, Mg, Na) and micronutrients (Mn, Zn, Cu, Se).The results show that the rind of pomegranate fruits (Punica L.) is a polycomplex property by chemical composition and a promising agent in the development of pharmacological drugs.