神经黑素
黑质
磁共振成像
帕金森病
医学
疾病
神经影像学
磁共振光谱成像
多巴胺能
成像生物标志物
痴呆
前驱期
正电子发射断层摄影术
神经科学
病理
多巴胺
放射科
内科学
心理学
作者
Trina Mitchell,Stéphane Lehéricy,Shannon Chiu,Antonio P. Strafella,A. Jon Stoessl,David E. Vaillancourt
出处
期刊:JAMA Neurology
[American Medical Association]
日期:2021-08-30
卷期号:78 (10): 1262-1262
被引量:208
标识
DOI:10.1001/jamaneurol.2021.1312
摘要
Imaging biomarkers for various stages of PD are readily available to be used as outcome measures in clinical trials and are potentially useful in multimodal combination with routine clinical assessment. This Review provides a critically important template for considering disease stage when implementing diagnostic and progression biomarkers in both clinical trials and clinical care settings.
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