OBJECTIVES: To study the risk factors associated with the need for mechanical ventilation in children with Guillain-Barré syndrome (GBS). METHODS: The medical data of 107 children with GBS were retrospectively reviewed. According to whether mechanical ventilation was required, the children were divided into a mechanical ventilation group with 16 children and a non-mechanical ventilation group with 91 children. The risk factors associated with the need for mechanical ventilation in children with GBS were identified by a multivariate logistic regression analysis. RESULTS: <0.05). CONCLUSIONS: .