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Comparative Morbidity Profile of Elective vs Therapeutic Neck Dissection

医学 回顾性队列研究 外科 解剖(医学) 子群分析 人口 内科学 置信区间 环境卫生
作者
Quinn A. Dunlap,James Reed Gardner,Amanda C. Ederle,Deanne King,Maya Merriweather,Emre A. Vural,Mauricio Alejandro Moreno
出处
期刊:Otolaryngology-Head and Neck Surgery [Wiley]
卷期号:166 (2): 327-333 被引量:7
标识
DOI:10.1177/01945998211008915
摘要

Objective Neck dissection (ND) is one of the most commonly performed procedures in head and neck surgery. We sought to compare the morbidity of elective ND (END) versus therapeutic ND (TND). Study Design Retrospective chart review. Setting Academic tertiary care center. Methods Retrospective chart review of 373 NDs performed from January 2015 to December 2018. Patients with radical ND or inadequate chart documentation were excluded. Demographics, clinicopathologic data, complications, and sacrificed structures during ND were retrieved. Statistical analysis was performed with χ 2 and analysis of variance for comparison of categorical and continuous variables, respectively, with statistical alpha set a 0.05. Results Patients examined consisted of 224 males (60%) with a mean age of 60 years. TND accounted for 79% (n = 296) as compared with 21% (n = 77) for END. Other than a significantly higher history of radiation (37% vs 7%, P <. 001) and endocrine pathology (34% vs 2.6%, P <. 001) in the TND group, no significant differences in demographics were found between the therapeutic and elective groups. A significantly higher rate of structure sacrifice and extranodal extension within the TND group was noted to hold in overall and subgroup comparisons. No significant difference in rate of surgical complications was appreciated between groups in overall or subgroup analysis. Conclusion While the significantly higher rate of structure sacrifice among the TND population represents an increased morbidity profile in these patients, no significant difference was found in the rate of surgical complications between groups. The significant difference seen between groups regarding history of radiation and endocrine pathology likely represents selection bias.
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