Synthesis of Roxithromycin

Roxithromycin is a kind of semi-synthetical antibiotic drugs of large ring lactone. Roxithromycin is produced basically by synthesize from β-methoxy ethoxy methyl chloride and Oximido erythrocin that has been oximated from Sulfocyanic acid and Erythromycin. the technical course of Roxithromycin preparation referred to the literature at home and abroad was ameliorated.