Objectives To study the application value of calculus interception net in the ureteroscopic pneumatic lithotripsy for the treatment of upper and middle ureteral calculus. Methods 48 (32 males and 16 females) patients with upper and middle ureteral calculus underwent transureteroscopic pneumatic lithotripsy with calculus interception net, among which, 32 were male and 16 were female. The diameter of ureteral calculus were 0.7~2.0 cm. There were 18 upper ureteral calculus and 30 middle ureteral calculus; 22 left-side ureteral calculus and 26 right side ureteral calculus. There were 6 both-sides crinosity calculus accompanied with 4 cases of vesical calculus. Results Among 48 cases, there were 17 cases of successful macadam of upper ureteral calculus (94.4%) and 1 case of upward calculus; 29 cases of middle ureteral calculus (96.6%) and 1 case of ineffective calculus interception. Conclusions Calculus In- terception Net could effectively prevent calculus upward during ureteroscopic pneumatic lithotripsy process, with the advantages of conveniency, safety and high-efficiency, which is worth to be promoted in clinical application.