Synthesis and Characterization of Polyethylene Glycol ω-amino acid

A new kind of polyethylene glycol ω-amino acid was prepared from polyethylene glycol.The synthetic procedure combined solution phase synthesis and solid phase synthesis.This compound was not reported previously.The structure of the target compound was confirmed by IR,1H NMR spectrum and MS.This method had the advantages of starting with readily available materials,reacting under mild conditions,obtained in high yield with short synthetic route and simple purification.This kind of polyethylene glycol ω-amino can widely used in the targeting drugs synthesis,biosensing peptide synthesis and so on.