Palladium-catalyzed cascade reactions of enynones and isocyanides: access towards functionalized ketenimine and its application

Palladium-catalyzed cascade reactions of enynones and isocyanides have been disclosed. This strategy allows for the synthesis of structurally unusual furan-incorporated ketenimines, which are stable and can undergo a formal [4+1] annulation with another isocyanide to yield indenone derivatives.