In this study, 16 moderate alcohol consumers without structural liver disease ceased alcohol intake for 1 month and underwent liver measurements at three time points. Gamma-glutamyl transferase, although within the normal range, decreased significantly after abstinence and increased after the resumption of alcohol consumption. Short summary: In this study in healthy moderate alcohol consumers, we observe that one month of alcohol abstinence results in decreased gamma-glutamyl transferase levels, which return to baseline levels after resumption of alcohol consumption.