化学
分子内力
氧化还原
催化作用
氢键
分子
铜
组合化学
联轴节(管道)
药物化学
立体化学
光化学
有机化学
机械工程
工程类
作者
Guangzhe Li,Guangsuo Yu,Chengdong Wang,Taiki Morita,Xuhai Zhang,Hiroyuki Nakamura
摘要
Intramolecular hydroarylation-redox cross-dehydrogenative coupling of N-propargylanilines with phosphite diesters proceeded in the presence of Cu(I)-catalysts (20 mol%) to selectively give 2-phosphono-1,2,3,4-tetrahydroquinolines in good yields with 100% atomic utilization. P-H and two C-H bonds are activated at once and these hydrogen atoms are trapped by a propargylic triple bond in the molecule.
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