医学
银屑病性关节炎
内科学
接收机工作特性
中性粒细胞与淋巴细胞比率
胃肠病学
淋巴细胞
疾病
免疫系统
免疫学
作者
Ayşe Bahar Keleşoğlu Dinçer,Serdar Sezer
出处
期刊:JCPSP. Journal of the College of Physicians & Surgeons Pakistan
[College of Physicians and Surgeons Pakistan]
日期:2022-06-01
卷期号:32 (06): 773-778
被引量:14
标识
DOI:10.29271/jcpsp.2022.06.773
摘要
To assess the utility of systemic immune inflammation index (SII) in predicting disease activity in psoriatic arthritis (PsA) patients.A descriptive study.Dışkapı Yıldırım Beyazıt Research and Training Hospital, Ankara, Turkey, from October 2020 to September 2021.This study included 106 PsA and 103 age and gender-matched healthy individuals. Neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), monocyte to lymphocyte ratio (MLR), and SII were calculated from complete blood count parameters. The PsA disease activity was assessed by using disease activity score-ESR and DAS-CRP based on 28 joints and the Disease Activity in Psoriatic Arthritis (DAPSA) scores. The receiver operating characteristic (ROC) curve was performed to evaluate the utility of SII in determining disease activity in PsA patients.The NLR, PLR, MLR, and SII were significantly higher in PsA patients compared to healthy control (p=0.013, p=0.019, p=0.012, and p=0.002, respectively). There were statistically significant positive correlations between the DAS28-ESR, DAS28-CRP, and DAPSA and SII (p<0.001, p<0.001, and p<0.001 respectively). The SII values were significantly higher in PsA patients with moderate to severe disease activity according to DAPSA scores when compared to patients with remission or low disease activity (p<0.001). The cut-off value of 800x109/L was found for predicting disease activity in PsA.SII may be an easy, practical, economical, and readily accessible tool for monitoring disease activity and the efficacy of treatment in PsA patients.Blood cell count, Psoriatic arthritis, Systematic immune inflammation index (SII).
科研通智能强力驱动
Strongly Powered by AbleSci AI