近距离放射治疗
肿块切除术
乳腺癌
医学
放射治疗
医学物理学
癌症
放射科
乳房切除术
内科学
作者
Salvatore Cozzi,Matteo Augugliaro,Patrizia Ciammella,A. Botti,Valeria Trojani,M. Hassan Najafi,Gladys Blandino,Maria Paola Ruggieri,L. Giaccherini,Emanuele Alì,Federico Iori,Angela Sardaro,Sebastiano Finocchi Ghersi,Letizia Deantonio,Cristina Gutiérrez,C. Iotti,Lilia Bardoscia
出处
期刊:Cancers
[MDPI AG]
日期:2022-05-23
卷期号:14 (10): 2564-2564
被引量:8
标识
DOI:10.3390/cancers14102564
摘要
Breast cancer represents the second leading cause of cancer-related death in the female population, despite continuing advances in treatment options that have significantly accelerated in recent years. Conservative treatments have radically changed the concept of healing, also focusing on the psychological aspect of oncological treatments. In this scenario, radiotherapy plays a key role. Brachytherapy is an extremely versatile radiation technique that can be used in various settings for breast cancer treatment. Although it is invasive, technically complex, and requires a long learning curve, the dosimetric advantages and sparing of organs at risk are unequivocal. Literature data support muticatheter interstitial brachytherapy as the only method with strong scientific evidence to perform partial breast irradiation and reirradiation after previous conservative surgery and external beam radiotherapy, with longer follow-up than new, emerging radiation techniques, whose effectiveness is proven by over 20 years of experience. The aim of our work is to provide a comprehensive view of the use of interstitial brachytherapy to perform breast lumpectomy boost, breast-conserving accelerated partial breast irradiation, and salvage reirradiation for ipsilateral breast recurrence, with particular focus on the implant description, limits, and advantages of the technique.
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