Metabolic disorders in men with primary gout and hypertension syndrome

Aim. Hyperuricemia іs often associated with clusters of metabolic syndrome, that is why some authors determine hyperuricemia as a component of the metabolic syndrome. 50 men with primary gout combined with hypertension syndrome, 30 primary gout men without hypertension, 30 men with essential hypertension and 20 healthy men were examined for the study of the role of uric acid in metabolic status modification.Methods and results. We determined the main anthropometric indices, serum uric acid, fasting glucose, 2-hours glucose after tolerance test, total cholesterol, LDL, HDL, triglycerides. More expressed metabolic violations in patients with gout which was combined with arterial hypertension were found.Conclusion. Increasing of uric acid concentration was associated with high level of 2-hours glucose after tolerance test and affected to HDL rate decreasing and triglycerides level increase.