Mild and Efficient Construction of Nitrogen-Containing Heter-ocycles from Ortho-Ethynylbenzaldehydes and Anilines

A mild and transition-metal-free strategy for the synthesis of isoindolin-1-imines and isoquinolinium salts has been developed using ortho-ethynylbenzaldehydes and anilines. HFIP was employed as an effective promoter, facilitating nucleophilic addition...