A Wireless and Reusable OLED Patch for Accelerated In Vivo Skin Wound Healing

A fully wireless and reusable red organic light-emitting diode (OLED) patch was developed as a noninvasive platform for skin wound phototherapy. The device integrates a USB-C rechargeable battery, a flexible printed circuit board, and a red OLED emitter into a soft, skin-conformal form factor. The OLED delivers uniform 645 nm light with minimal heat (∼21 °C) and stable radiance (21.3 W/sr/m²) over 500 h. In a murine full-thickness wound model, a single session of irradiation (2.6-3.9 J/cm²) significantly accelerated wound closure, increased collagen synthesis, and enhanced epidermal differentiation. Immunohistochemical analysis further confirmed reduced inflammation and improved tissue maturation. Unlike previous OLED-based systems that required rigid encapsulation or wired power, this patch enables convenient, home-based light therapy without clinical supervision. The platform demonstrates strong potential as an electroceutical device for personalized dermatologic care and regenerative medicine.