血小板活化
CCL21型
细胞生物学
背景（考古学）
血小板
C-C趋化因子受体7型
信号转导
趋化因子
癌症研究
化学
趋化性
免疫学
血小板聚集
维斯坎
促炎细胞因子
动脉
原癌基因酪氨酸蛋白激酶Src
抗体
作者
Xin Liu,Peng Zhang,Zhexun Lia,Haichu Yu,Yonghong Li,Junjie Guo,Ning Zhang,Shimo Dai,Zhiyong Qi,Junbo Ge
标识
DOI：10.1161/circresaha.125.326784
摘要
CCL21 enhances platelet activation and atherothrombosis by binding to platelet CCR7 and thus activating downstream Gi and G13 signaling pathways. A CCL21 antibody can counteract these effects in the context of coronary artery disease, supporting its potential as a preventive therapy for thrombotic complications.
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