Lateral hypothalamic control of a spatially organized striatal dopamine landscape during consummatory behavior

Data and code archive for: "Lateral hypothalamic control of a spatially organized striatal dopamine landscape during consummatory behavior" Gordon-Fennell A, Benowitz BM, Barbakh JM, Montequin I, Campuzano A, Stevenson HP, Lu E, Hjort MM, Ancell E, Critz M, Witten D, Stuber GD. This archive contains the analysis code and data supporting all figures and statistics in the paper. Fiber photometry recordings of dopamine signaling were acquired across seven striatal subregions (NAcCR, NAcCC, NAcShL, NAcShM, DMS, DLS, TS) and the lateral hypothalamus (LHA-GABA, LHA-Glut) in mice performing a multi-spout brief-access taste task. Experiments include dual-color LHA photometry, multi-site striatal GRAB-DA photometry paired with LHA optogenetic stimulation and inhibition, local striatal DA propagation tests, and closed-loop terminal stimulation during licking behavior. Archive contents: R/RMarkdown figure scripts (analysis_and_plots/) and preprocessing pipeline (pipeline/) for full reproduction of all manuscript figures Pre-computed summary CSVs for all figure panels Full preprocessed session-level fiber photometry and behavioral data (data/sessions/) Aggregated cross-session summary files (data/combined_setid/) GLM signal/predictor matrices and permutation null distributions Compiled statistics workbook (stats_compilation/stats_compiled.xlsx; 86 sheets, one per panel) Conda environment specification and R package version snapshot (coding_environments/) See README.md for a full description of the repository structure and instructions for reproducing figures from the pre-computed CSVs or from raw session data.