Oxygen-carrying acid-responsive Cu/ZIF-8 for photodynamic antibacterial therapy against cariogenic Streptococcus mutans infection

Acid-induced demineralization caries is the most common oral microbial infectious disease. O 2 -Cu/ZIF-8@Ce6/ZIF-8@HA (OCZCH) as an intelligent acid-responsive photosensitive nanomaterial, was chosen to adapt to the acidic caries microenvironment for inactivating Streptococcus mutans .