化学
废止
区域选择性
钌
催化作用
咪唑
烯烃
戒指(化学)
级联
级联反应
药物化学
立体化学
组合化学
光化学
有机化学
色谱法
作者
Rekha Thakur,Kamaldeep Paul
标识
DOI:10.1021/acs.joc.3c02947
摘要
We report ruthenium(II)-catalyzed sequential C–H/N–H alkenylation cascade of phenanthroimidazole and alkenes to form novel phenanthroimidazoisoindol acrylates via dual C–H activation and aza-Michael reaction. The two nitrogen atoms of the imidazole ring act as directing groups for regioselective dual sequential ortho C–H activation. These polycyclic N-heterocycles were evaluated for their photophysical properties.
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