二肽
苯丙氨酸
内分泌学
骨骼肌
内科学
食欲
肥胖
医学
化学
氨基酸
生物化学
作者
Jens Lund,Christoffer Clemmensen,Thue W. Schwartz
出处
期刊：Cell Metabolism
[Cell Press]
日期：2022-08-01
卷期号：34 (8): 1085-1087
被引量：11
标识
DOI：10.1016/j.cmet.2022.07.007
摘要
Lactate released from skeletal muscle during high-intensity exercise gives rise to a surge in circulating lactate-derived pseudo-dipeptide metabolites including N-lactoyl-phenylalanine (Lac-Phe). In a recent Nature paper, Li et al. use genetic and pharmacological evidence to now propose Lac-Phe to be an "exercise hormone" that suppresses appetite and obesity.
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