Dysfunction of a lepidopteran conserved gene, BmBLOC1S6 , causes a translucent larval integument in the silkworm, Bombyx mori

Our results showed that BmBLOC1S6 is responsible for the oh phenotype in silkworms and is conserved during lepidopteran evolution. This study may help us better clarify uric acid granules formation in the epidermis, explore their function in UV resistance and identify a potential molecular target for lepidopteran pest control. © 2025 Society of Chemical Industry.