Novel Preclinical Study of Galloylquinic Acid Compounds from <i>Copaifera lucens</i> with Potent Antifungal Activity against Vaginal Candidiasis Induced in a Murine Model via Multitarget Modes of Action
抗真菌
白色念珠菌
微生物学
生物
作者
Lamiaa A. Al-Madboly,Mohamed Abd El-Salam,Jairo Bastos,Safinaz H. El-Shorbagy,Rasha M. El-Morsi
出处
期刊:Microbiology spectrum [American Society for Microbiology] 日期:2022-08-16卷期号:10 (5)
Our work presents a new perspective on the potential use of GQAs as safe and highly effective phytochemicals against MDR C. albicans . This microorganism colonizes the human vaginal epithelium, causing vaginal candidiasis, a condition characterized by recurrent pathogenicity and tolerance to traditional antifungal therapy.