Surface‐Engineered Orthopedic Implant to Break the Antimicrobial‐Osteogenic Paradox at Biointerfaces in the “Race for the Surface”

-mediated signaling pathways. Moreover, Ti-AQs can drive immunomodulation biased macrophages toward pro-repair M2 polarization. In vivo evaluations in an implant-associated infection modal confirmed that Ti-AQ-2 inhibited infection at the early stage and enhanced bone-implant integration at the late stage. This work presents a facile strategy to regulate the surface performances for developing of antibacterial implants with high biocompatibility and bioactivity.