孕烷
孕烯醇酮
雄甾酮
化学
类固醇
芳香化酶
生物合成
内分泌学
孕酮受体
内科学
激素
雌酮
内生
生物
胆固醇侧链裂解酶
生物化学
酶
立体化学
细胞色素P450
新陈代谢
医学
雌激素受体
癌症
乳腺癌
出处
期刊:Steroids
[Elsevier BV]
日期:2015-08-14
卷期号:103: 145-152
被引量:40
标识
DOI:10.1016/j.steroids.2015.08.007
摘要
In plants androstanes, estranes, pregnanes and corticoids have been described. Sometimes 17β-estradiol, androsterone, testosterone or progesterone were summarized as sex hormones. These steroids influence plant development: cell divisions, root and shoot growth, embryo growth, flowering, pollen tube growth and callus proliferation. First reports on the effect of applicated substances and of their endogenous occurrence date from the early twenties of the last century. This caused later on doubts on the identity of the compounds. Best investigated is the effect of progesterone. Main steps of the progesterone biosynthetic pathway have been analyzed in Digitalis. Cholesterol-side-chain-cleavage, pregnenolone and progesterone formation as well as the stereospecific reduction of progesterone are described and the corresponding enzymes are presented. Biosynthesis of androstanes, estranes and corticoids is discussed. Possible progesterone receptors and physiological reactions on progesterone application are reviewed.
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