整合素
膜联蛋白A2
细胞生物学
整合素αM
脂筏
整合素,β6
CD49c
化学
Cypa
血小板活化
分子生物学
膜联蛋白
生物
信号转导
生物化学
血小板
受体
免疫学
细胞
亲环素A
作者
Chenghu Zhang,Ting Zhou,Zhipeng Chen,Yan Meng,Bochuan Li,Huizhen Lv,Chunjiong Wang,Song Xiang,Lei Shi,Yi Zhu,Ding Ai
出处
期刊:Circulation Research
[Lippincott Williams & Wilkins]
日期:2020-07-16
卷期号:127 (8): 1074-1090
被引量:114
标识
DOI:10.1161/circresaha.120.316857
摘要
Our data elucidate a novel endothelial mechanotransduction molecular mechanism linking atheroprone flow and activation of integrin α5β1, thereby identifying a class of potential therapeutic targets for atherosclerosis. Graphic Abstract: An graphic abstract is available for this article.
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