青光眼
医学
疾病
眼压
黄斑变性
风险因素
心理干预
眼科
药品
生物信息学
重症监护医学
内科学
药理学
生物
精神科
作者
Foroogh Fahmideh,Nicoletta Marchesi,Annalisa Barbieri,Stefano Govoni,Alessia Pascale
标识
DOI:10.1016/j.survophthal.2021.09.002
摘要
Glaucoma is a major ocular neurodegenerative disease characterized by progressive retinal ganglion cells degeneration and sight loss. Current treatment options have been limited to reducing intraocular pressure (IOP), known as the leading risk factor for this disease; however, glaucoma can develop even with low or normal IOP and progress despite controlling IOP values. Lifestyle, dietary habits, and supplementation may influence some of the risk factors and pathophysiological mechanisms underlying glaucoma development and progression; thus, the role of this complementary and alternative medicine in glaucoma has received great interest from both patients and ophthalmologists. We provide a summary of the current evidence concerning the relationship between lifestyle, dietary habits, and effects of supplements on the incidence and progression of glaucoma and their targets and associated mechanisms. The data suggest the existence of a therapeutic potential that needs to be further explored with both preclinical and rigorous clinical studies.
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