一氧化氮
医学
急性肾损伤
氧化应激
内皮型一氧化氮合酶
一氧化氮合酶
重编程
肾
病理生理学
近曲小管
药理学
生物信息学
内科学
生物化学
生物
细胞
伊诺斯
作者
Pierre‐Yves Martin,Sophie de Seigneux
标识
DOI:10.1038/s41581-019-0113-z
摘要
New findings demonstrate that endothelial nitric oxide synthase regulates major metabolic pathways in the kidney proximal tubule, which confers protection against oxidative stress during acute kidney injury (AKI). These findings give new insights into AKI pathophysiology and nitric oxide biology, and identify new targets for the treatment of AKI.
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