2-Methyl-2-propanol as solvent for o-iodoxybenzoic acid (IBX) oxidation of 1˚ alcohols to aldehydes

2-Methyl-2-propanol has been demonstrated to be an effective solvent for IBX oxidation of 1˚ alcohols to the corresponding aldehydes. IBX has a measurable, but low, solubility in 2-methyl-2-propanol and thus partially avoids the drawbacks inherent in the solubility problems associated with IBX without resorting to less desirable solvents. This may be particularly useful where solubility of the alcohol is also at issue.