前列腺癌
基因沉默
癌症研究
DNA甲基化
癌症
二氢睾酮
雄激素受体
生物
选择性拼接
RNA剪接
前列腺
雄激素
内分泌学
基因亚型
基因表达
遗传学
基因
核糖核酸
激素
作者
Xiaomei Gao,Charles S. Dai,Shengsong Huang,Jingjie Tang,Guoyuan Chen,Jianneng Li,Ziqi Zhu,Xuyou Zhu,Shuirong Zhou,Yuan‐Yuan Gao,Zemin Hou,Zijun Fang,Chengdang Xu,Jianyang Wang,Denglong Wu,Nima Sharifi,Zhenfei Li
标识
DOI:10.1158/1078-0432.ccr-18-2392
摘要
Our findings provide evidence of the clinical relevance, significance, and regulation of HSD17B2 in prostate cancer progression, which might provide new strategies for clinical management by targeting the functional silencing mechanisms of HSD17B2.See related commentary by Mostaghel, p. 1139.
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