医学
汽车T细胞治疗
多发性骨髓瘤
癌症研究
抗原
细胞疗法
肿瘤科
耐火材料(行星科学)
免疫学
T细胞
嵌合抗原受体
细胞
生物
免疫系统
遗传学
天体生物学
作者
Noopur Raje,Jesús G. Berdeja,Yi Lin,David S. Siegel,Sundar Jagannath,Deepu Madduri,Michaela Liedtke,Jacalyn Rosenblatt,Marcela V. Maus,Ashley Turka,Lyh Ping Lam,Richard A. Morgan,Kevin M. Friedman,Monica Massaro,Julie Wang,Greg Russotti,Zhihong Yang,Timothy B. Campbell,Kristen Hege,Fabio Petrocca,M. Travis Quigley,Nikhil C. Munshi,James N. Kochenderfer
标识
DOI:10.1056/nejmoa1817226
摘要
Preclinical studies suggest that bb2121, a chimeric antigen receptor (CAR) T-cell therapy that targets B-cell maturation antigen (BCMA), has potential for the treatment of multiple myeloma.
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