化学
烟气脱硫
试剂
烷基
产量(工程)
芳基
电泳剂
氧化磷酸化
有机化学
Pummer重排
药物化学
氟化物
催化作用
无机化学
生物化学
冶金
材料科学
醋酸酐
作者
Verena Hugenberg,Günter Haufe
标识
DOI:10.1016/j.jfluchem.2010.06.010
摘要
Alkyl 2-arylthio-2,2-difluoroacetates are synthesized in 52–77% yield from alkyl 2-(arylthio)acetates via two succeeding fluoro-Pummerer rearrangements using the reagents combination of N-haloimides as electrophiles and excess Py·9HF as the fluoride source at room temperature. Subsequent treatment of the formed fluorinated thioethers with the same reagents at elevated temperature gave alkyl trifluoroacetates in almost quantitative yield under optimised conditions by oxidative desulfurization–fluorination.
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