Achievements in the area of research into the micromanipulation of objects within the micron range are considered. The similarities and differences between objects in the macro-and micromanipulation area are discussed. The author describes the adhesive mechanisms that act in the microworld in adhesion to hard surfaces in the presence of liquid adhesives and without their participation. Theoretical models are presented for estimating the adhesion forces arising between micro-objects and the area of micromanipulation, as well as some practical experiments with mechanical and biological objects in regard to their grasping and clinging to surfaces.