Clinical study of partial cystectomy combined with chemotherapy for muscle-invasive bladder cancer

Background and purpose:For muscle-invasive bladder caner patients,the recommended treatment is radical cystectomy.While some patients are not suitable or unwilling to this treatment,bladder preserving treatment provides another choice.This research aimed to assess the curative effect,influencing factors of partial cystectomy plus chemotherapy for muscle-invasive bladder cancer.Methods:From Jan.2002 to Apr.2005,52 patients with muscle-invasive bladder cancer underwent partial cystectomy plus chemotherapy(PC group),contrast to 47 patients which underwent radical cystectomy(RC group).The overall survival rates(OS) of the two groups were analyzed.Results:There is no significant difference of overall survival between the two groups(P=0.279).For stage T3 and recurrent patients the PC group had significantly lower survival rates than RC group(P=0.048).Conclusion:Partial cystectomy plus chemotherapy provides a choice for the treatment of muscle-invasive bladder cancer.