19 species of moulds that will be used in the antifungal experiments are separated from the mildewed pigskins including pickled pelts,wet blue,dyed pelts and finished leather.Dimethyl fumarate(B),propylp-hydroxybenzoate(C),cinnamic acid(D),isothiozolone(E) and sample A(A) which was synthesized by the lab were chosen as the active ingredients of the combined antifungal agents and their antifungal activity to these moulds was tested.Results show that the order of their antifungal activity is EADCB.