Pharmacodynamics of TongLuo ChaJi in Treating Soft Tissue Injury

Objective: To verify the efficacy of TongLuo ChaJi in treating soft tissue injury from molecular biology,histomorphology and pathology by treating animal models with TongLuo ChaJi in order to provide theoretical evidence for clinical application.Method: All 50 rats were assigned randomly into three groups.Five rats were chosen from each group to collect blood and injured soft tissue.Pharmacological actions of associated drugs were observed on three time phases at the first day,third day and fifth day after successfully establishing the models.Result: Comparison between model group and TongLuo ChaJi group showed remarkable difference in concentrations of interleukin(IL-1) and prostaglandin(PGE2) at the second to the third survey(P0.05);local injured soft tissue nearly restored to normal tissue;TongLuo ChaJi and ZhengGuShui could promote the elimination of local swelling,ecchymosis and bruising,both groups indicated remarkable difference compared with model control group(P0.05).Conclusion: TongLuo ChaJi suggested notable rehabilitation for experimental rat with soft tissue injury.