Dimple fracture under mixed mode loading condition is studied experimentally and numerically. By the mixed mode loading, it is found that fracture surface becomes much rougher than that of mode I fracture. It is also found that ductile fracture growth direction deviates from the original plane. It becomes clear that there are two factors affecting ductile fracture processes, one is mixed mode ratio and another is thickness effect. Three-dimensional finite element analyses are conducted to study effects of these factors. For the simulation of ductile fracture, Gurson’s constitutive equation is used with large deformation theory. These numerical results agree with experimental observation very well qualitatively.