化学
转移加氢
催化作用
氢
锌
还原剂
组合化学
转化(遗传学)
金属
戒指(化学)
有机化学
钌
生物化学
基因
作者
Guoli Shen,Jingchao Chen,D. Xu,Xia Zhang,Yong‐Gui Zhou,Baomin Fan
出处
期刊:Organic Letters
[American Chemical Society]
日期:2019-02-12
卷期号:21 (5): 1364-1367
被引量:31
标识
DOI:10.1021/acs.orglett.9b00059
摘要
The asymmetric transfer hydrogenation of heterobicyclic alkenes was accomplished by using water as the sole hydrogen source. The transformation was co-catalyzed by Pd(OAc)2/Zn(OTf)2 dual catalyst with metallic zinc as reducing agent. Various azabenzonorbornadienes and oxabenzonorbornadienes were transformed to the corresponding chiral 1,2-dihydronaphthalenes by the asymmetric reductive ring-opening reactions with good to excellent enantioselectivities.
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