肉眼
贵金属
纳米颗粒
纳米技术
材料科学
表面等离子共振
分析物
纳米材料
表征(材料科学)
计算机科学
金属
化学
检出限
色谱法
冶金
作者
Xiaoming Ma,Shan He,Bin Qiu,Fang Luo,Longhua Guo,Zhenyu Lin
出处
期刊:ACS Sensors
[American Chemical Society]
日期:2019-03-21
卷期号:4 (4): 782-791
被引量:103
标识
DOI:10.1021/acssensors.9b00438
摘要
Noble metal nanoparticle-based colorimetric sensors have become powerful tools for the detection of different targets with convenient readout. Among the many types of nanomaterials, noble metal nanoparticles exhibit extraordinary optical responses mainly due to their excellent localized surface plasmon resonance (LSPR) properties. The absorption spectrum of the noble metal nanoparticles was mostly in the visible range. This property enables the visual detection of various analytes with the naked eye. Among numerous color change modes, the way that different concentrations of targets represent vivid color changes has been brought to the forefront because the color distinction capability of normal human eyes is usually better than the intensity change capability. We review the state of the art in noble metal nanoparticle-based multicolor colorimetric strategies adopted for visual quantification by the naked eye. These multicolor strategies based on different means of morphology transformation are classified into two categories, namely, the etching of nanoparticles and the growth of nanoparticles. We highlight recent progress on the different means by which biocatalytic reactions mediated LSPR modulation signal generation and their applications in the construction of multicolor immunoassays. We also discuss the current challenges associated with multicolor colorimetric sensors during actual sample detection and propose the future development of next-generation multicolor qualification strategies.
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