Development of Synthetic Vaccines against Antitumour and HIV having Lipid A Analogs as a Synthetic Immunoadjuvant.

This article describes our recent development of completely synthetic vaccines based on tumour- and HIV-associated carbohydrate and peptide antigens having N-tetradecanoyl L-seryl-β-alanine-containing D-glucosamine derivatives structurally related to lipid A as efficient synthetic immunoadjuvants.