广告
肽
药理学
药代动力学
药品
化学
医学
计算生物学
生物化学
生物
作者
Anders Sonesson,Inga Bjørnsdottir,Jesper Kammersgaard Christensen
出处
期刊:Xenobiotica
[Taylor & Francis]
日期:2021-12-02
卷期号:51 (12): 1470-1474
被引量:6
标识
DOI:10.1080/00498254.2021.2020377
摘要
Challenges and opportunities within peptide ADME (absorption, distribution, metabolism and elimination) were presented and discussed at the 3rd online workshop of the Peptide ADME Discussion Group (3rd of February 2021). This article summarises the presentations and discussions from this workshop.The following topics were covered:Peptide drug-drug interactionsImpact of septic shock on PK and PD of the peptide selepressinMS processing software for metabolite identification of peptidesProfiling of peptides in preclinical drug developmentStrategy for immunogenicity testing of peptidesIn vitro stability testing of peptides for inhalation and automated LC-MS.
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